Concave reagents

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Ulrich Lüning


Abstract

The concave geometry of enzymes is important for the high selectivity of their reactions. By analogy, the incorporation of standard reagents of organic chemistry into a concave environment gives concave reagents with a geometry resembling that of a light bulb in a lampshade. Selectivity enhancements have been realized in protonations, base catalysed reactions and metal ion catalysed reactions.


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