Oxidation of Isothiocyanates to Isocyanates using Dimethyldioxirane; Relevance to Biological Activity of Isothiocyanates†

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Nicola E. Davidson and Nigel P. Botting


Abstract

The reaction of organic isothiocyanates with dimethyldioxirane in acetone produces isocyanates in good yields, trapped out as the ureas by reaction with isopropylamine.


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