C-Nucleophilic Substitution of 5-Halo-1,2,3-thiadiazoles as an Approach to Fused Pyridones and Pyranones

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Evgeny V. Tarasov, Yury Yu. Morzherin, Suzanne Toppet, Wim Dehaen and Vasiliy A. Bakulev


Abstract

A new approach to the one-pot preparation of fused 1,2,3-thiadiazoles from 5-chloro-substituted derivatives, involving C-nucleophilic substitution followed by subsequent cyclization, has been found.