Reaction of Isoeugenol with Formaldehyde in Basic Medium: Formation of trans-4-(4-Hydroxy-3-hydroxymethyl-5-methoxy)-5-methyl-1,3-dioxane and its Transformation into the Tricyclo[5.2.2.0^2,6]undecane System†

Abstract

Formation of the title compound 3, via an unusual Prins-type reaction on isoeugenol with formaldehyde in alkaline medium, and its conversion into a tricyclo[5.2.2.0^2,6]undecane system 4 is described.

References

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