Regioselective Routes to Functionalised Piperazine-2,5-diones
(Note: The full text of this document is currently only available in the PDF Version )
Christina L. L. Chai and Alison R. King
Abstract
The regioselectivities observed in the reactions of bromopiperazine-2,5-diones with triethyl phosphite depend markedly on the N-substituents α to the brominated carbon atom.
References
A. K. Bhattacharya and G. Thyagarajan, Chem. Rev., 1981, 81, 415 Search PubMed.
(a) R. Kober and W. Steglich, Liebigs Ann. Chem., 1983, 599 Search PubMed;
(b) K. Burger, E. Heistracher, R. Simmerl and M. Eggersdorfer, Z. Naturforsch., Teil B, 1992, 47, 424 Search PubMed.
P. A. Chopard, V. M. Clark, R. F. Hudson and A. J. Kirby, Tetrahedron, 1965, 21, 1961 Search PubMed.
For examples, see
(a) J. F. Allen and O. H. Johnson, J. Am. Chem. Soc., 1955, 77, 2871 Search PubMed;
(b) H. I. Jacobson, M. J. Griffin, S. Preis and E. V. Jensen, J. Am. Chem. Soc., 1957, 79, 2608 Search PubMed.
C. L. L. Chai and A. R. King, Tetrahedron Lett., 1995, 36, 4295 Search PubMed.
Click here to see how this site uses Cookies. View our privacy policy here.