Template Aggregative Activation: Metal Salt-reinforcedComplex Bases in Arynic Synthesis†

Abstract

A substantial effect on the reactivity of a commoncomplex base is observed by the addition of metal salts MX_n (M=Mg, Zn, Cu, Zr); a template effect of thenew aggregates is proposed.

References

1. See for example: M. A. Zouaoui, A. Mouaddib, B. Jamart-Grégoire, S. Ianelli, M. Nardelli and P. Caubère, J. Org. Chem., 1991, 56, 4078 and references cited therein.
2. P. Caubère, Chem. Rev., 1993, 93, 2317.
3. P. Palmas, P. Tekely, B. Jamart-Grégoire, P. Caubère and D. Canet, J. Am. Chem. Soc., 1994, 116, 11 604.
4. P. Caubère, Rev. Heteroatom. Chem., 1991, 4, 78.
5. P. Caubère, N. Derozier and B. Loubinoux, Bull. Soc. Chim. Fr., 1971, 302.
6. See for example: Y. Ito, T. Konaike and T. Saegusa, J. Am. Chem. Soc., 1975, 97, 2912.
7. P. Caubère, G. Guillaumet and M. S. Mourad, Tetrahedron, 1973, 29, 1857 In the present work, yields of compounds 5 and 6 were determined by GC analyses and the 5∶6 ratio was confirmed by ¹H NMR analyses.
8. J. J. Brunet, L. Mordenti and P. Caubère, J. Org. Chem., 1978, 43, 4804.