View PDF Version
 
DOI: 10.1039/A701579H (Paper) Reference Section for: J. Chem. Res. (S), 1997, 250-251

Studies on Pyrazines. Part 33.1 Synthesis of 2,3-Diaminopyrazines via [1,2,5]Thiadiazolo[3,4-b]pyrazines

(Note: The full text of this document is currently only available in the PDF Version )

Nobuhiro Sato and Hajime Mizuno

Abstract

The syntheses of [1,2,5]thiadiazolo[3,4-b]pyrazine (3) and its methyl and/or phenyl derivatives as well as their reduction to 2,3-diaminopyrazines 4 are described.

References

  1. Part 32, see N. Sato and T. Matsuura, J. Chem. Soc., Perkin Trans. 1, 1996, 2345 Search PubMed.
  2. (a) G. B. Barlin, The Pyrazines, ed. A. Weissberger and E. C. Taylor, Interscience, New York, 1983, p. 35 Search PubMed; (b) A. E. A. Porter, in Comprehensive Heterocyclic Chemistry, ed. A. R. Katritzky and C. W. Rees, Pergamon, Oxford, vol. 3, 1984, p. 157 Search PubMed; (c) N. Sato, in Comprehensive Heterocyclic Chemistry, ed. A. R. Katritzky, C. W. Rees and E. F. V. Scriven, Pergamon, Oxford, 2nd edn., 1996, vol. 6, p. 233 Search PubMed.
  3. N. Sato and J. Adachi, J. Org. Chem., 1978, 43, 341 CrossRef CAS.
  4. A. P. Komin and M. Carmack, J. Heterocycl. Chem., 1976, 13, 13 CAS.
  5. M. T. Clark and I. J. Gilmore, UK Pat., 2 122 492, 1984(Chem. Abstr., 1984, 100, 204 992t) Search PubMed.
  6. (a) A. P. Komin, R. W. Street and M. Carmack, J. Org. Chem., 1975, 40, 2749 CrossRef CAS; (b) P. Camilleri, B. Odell and P. O'Neill, J. Chem. Soc., Perkin Trans. 2, 1987, 1671 RSC.
  7. (a) S. Mataga, H. Eguchi, K. Takahashi, T. Hatta and M. Tashiro, Bull. Chem. Soc. Jpn., 1989, 62, 3127; (b) S. Mataga, Y. Ikezaki, K. Takahashi, A. Torii and M. Tashiro, Heterocycles, 1992, 33, 791.
  8. N. Sato, T. Matsuura and N. Miwa, Synthesis, 1994, 931 CrossRef CAS.
  9. F. G. McDonald and R. C. Ellington, J. Am. Chem. Soc., 1947, 69, 1034 CrossRef CAS.
  10. R. C. Ellingson and R. L. Henry, J. Am. Chem. Soc., 1948, 70, 1257 CrossRef CAS.
  11. J. Adachi and N. Sato, J. Org. Chem., 1972, 37, 221 CrossRef CAS.