DOI: 10.1039/A608035I
(Paper)
Reference Section for: J. Chem. Res. (S), 1997, 118-119
Simple and Condensed β-Lactams. Part 28.1 The Synthesis of C-Methylcarumonams and of a Related Bis(carbamate)
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József Fetter, Ferenc Bertha, Károly Lempert, Attila Sápi and Mária Kajtár-Peredy
Abstract
Racemic carumonam analogues 2a–d are synthesised and found to be devoid of any bacterial activity; NaBH4 reduction of 18 affords both epimers of 8c with the (3RS,4RS)-4-[(1RS)] epimer as the main product, and cyclocondensation of phthalimidoacetyl chloride with racemic imine 14 gives rise to the formation of (3RS,4RS)-4-[(1RS)]-15 as a single epimer.
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