Phase-transfer-catalysed Ring Opening of Cyclohexene Oxide by Phenylacetonitrile Carbanion in the Presence of Lithium Salts†

Abstract

Lithium cation assisted nucleophilic ring opening of cyclohexene oxide, by phenylacetonitrile carbanions, under phase-transfer conditions giving rise to a diastereoisomeric mixture of trans-γ-hydroxynitriles 7 and 8 is reported.

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