DOI: 10.1039/A600184J
(Paper)
Reference Section for: J. Chem. Res. (S), 1997, 154-155
Synthesis and Biological Evaluation of Some New Fused Quinazoline Derivatives
(Note: The full text of this document is currently only available in the PDF Version )
Salah S. Ibrahim, Ali M. Abdel-Halim, Yassien Gabr, Soummaia El-Edfawy and Reda M. Abdel-Rahman
Abstract
We report that biologically active fused quinazolines have been synthesized via treatment of 3-(N-acyl/ aroylamino)quinazolin-4(3H)-ones (2) with various nucleophilic reagents; some of the products showed moderate antibacterial activity.
References
- P. Mishra, P. N. Gupta and A. K. Shakya, J. Indian Chem Soc., 1991, 68, 618 Search PubMed.
- R. M. Abdel-Rahman, Indian J. Chem., 1988, 27B, 548 Search PubMed.
- M. Seada, R. M. Abdel-Rahman and M. Abdel-Megid, Indian J. Heterocycl. Chem., 1993, 9 Search PubMed.
- O. H. Wheeler and P. H. Gore, J. Org. Chem., 1961, 26, 3298 CrossRef.
- T. J. Mackie and J. E. MacCartheny, Practical Medical Microbiology, 30th edn., Churchill Livingstone, Edinburgh, London, New York, 1989 Search PubMed.
- S. A. Abdel-Aziz, H. A. Allimony, H. M. El-Shaaer, U. F. Ali and R. M. Abdel-Rahman, Phosphorus, Sulfur Silicon Relat. Elem., 1996, 113, 67 CAS.