View PDF Version
 
DOI: 10.1039/A701554B (Paper) Reference Section for: J. Anal. At. Spectrom., 1997, 12, 1047-1052

Speciation of Six Arsenic Compounds Using High-performance Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry With Sample Introduction by Thermospray Nebulization

(Note: The full text of this document is currently only available in the PDF Version )

STEVEN SAVERWYNS, XINRONG ZHANG, FRANK VANHAECKE, RITA CORNELIS, LUC MOENS and RICHARD DAMS

Abstract

A hyphenated technique for the determination of AsIII, AsV, arsenobetaine (AsB), arsenocholine (AsC), monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) has been developed by coupling an anion-exchange column to an inductively coupled plasma mass spectrometer, using an in-house developed thermospray nebulizer (TN) as an interface. Optimisation of the chromatographic conditions led to baseline separation of the signals from the six aforementioned compounds in approximately 10 min, using isocratic elution. Application of the TN offered a ten-fold improvement in sensitivity in comparison with the standard pneumatic nebulizer. To prevent clogging of the torch and to slow down deposit formation on the sampling cone, use was made of a second HPLC pump and a switching valve, allowing rinsing with HNO3 between two measurements. Detection limits were also improved and were in the range 0.04–0.12 µg l-1 as arsenic. Finally, the technique developed was used for the analysis of several mineral waters and urine samples. The improved sensitivity was also obtained for real samples. In the mineral waters analysed only AsV could be detected. In the ten-fold diluted urine samples, all aforementioned arsenic compounds were present, except for AsC, which could not be detected.

References

  1. H. Yamauchi and B. A. Fowler, in Arsenic in the Environment, Part II, ed. Nriagu, J. O., Wiley, New York, 1994, p. 35 Search PubMed.
  2. S. Branch, L. Ebdon and P. O'Neill, J. Anal. At. Spectrom., 1994, 9, 33 RSC.
  3. B. S. Sheppard, J. A. Caruso, D. T. Heitkemper and K. A. Wolnik, Analyst, 1992, 117, 971 RSC.
  4. S. H. Hansen, E. H. Larsen, G. Pritzl and C. Cornett, J. Anal. At. Spectrom., 1992, 7, 629 RSC.
  5. D. Heitkemper, J. Creed and J. Caruso, J. Anal. At. Spectrom., 1989, 4, 279 RSC.
  6. D. Beauchemin, K. W. M. Siu, J. W. McLaren and S. S. Bermann, J. Anal. At. Spectrom., 1989, 4, 285 RSC.
  7. K. E. LaFreniere, V. A. Fassel and D. E. Eckels, Anal. Chem., 1987, 59, 879 CrossRef CAS.
  8. J. J. Thompson and R. S. Houk, Anal. Chem., 1986, 58, 2541 CrossRef.
  9. P. Thomas and K. Sniatecki, Fresenius' J. Anal. Chem., 1995, 351, 410 CrossRef CAS.
  10. P. Thomas and K. Sniatecki, J. Anal. At. Spectrom., 1995, 10, 615 RSC.
  11. P. Teräsahde, M. Pantsar-Kallio and P. K. G. Manninen, poster presentation at the HTC-4 symposium, 7–9 February 1996, Bruges, Belgium.
  12. X. Zhang, R. Cornelis, J. De Kimpe and L. Mees, Anal. Chim. Acta, 1996, 319, 177 CrossRef CAS.
  13. D. Vélez, N. Ybáñez and R. Montoro, J. Anal. At. Spectrom., 1996, 11, 271 RSC.
  14. J. Costa-Fernandez, F. Lunzer, R. Pereiro-Garcia, A. Sanz-Medel and N. Bordel-Garcia, J. Anal. At. Spectrom., 1995, 10, 1019 RSC.
  15. G. Pauret, R. Rubio and A. Padró, Fresenius' J. Anal. Chem., 1991, 340, 157 CrossRef CAS.
  16. S. A. Pergantis, E. M. Heitmar and T. A. Hinners, Anal. Chem., 1995, 67, 4530 CrossRef CAS.
  17. H. Ding, J. Wang, J. G. Dorsey and J. A. Caruso, J. Chromatogr. A., 1995, 694, 425 CrossRef CAS.
  18. J. J. Thompson and R. S. Houk, Anal. Chem., 1986, 58, 2541 CrossRef.
  19. R. I. Botto and J. J. Zhu, J. Anal. At. Spectrom., 1994, 9, 905 RSC.
  20. N. Jakubowski, I. Feldmann, D. Stüwer and H. Berndt, Spectrochim. Acta, Part B, 1992, 47, 119 CrossRef.
  21. H. Berndt and J. Yáñez, J. Anal. At. Spectrom., 1996, 11, 703 RSC.
  22. F. Vanhaecke, M. Van Holderbeke, L. Moens and R. Dams, J. Anal. At. Spectrom., 1996, 11, 543 RSC.
  23. H. Vanhoe, L. Moens and R. Dams, J. Anal. At. Spectrom., 1994, 9, 815 RSC.
  24. H. Vanhoe, S. Saverwijns, M. Parent, L. Moens and R. Dams, J. Anal. At. Spectrom., 1995, 10, 575 RSC.
  25. C. Thomas, N. Jakubowski, D. Stüwer and J. A. C. Broekaert, J. Anal. At. Spectrom., 1995, 10, 583 RSC.
  26. J. A. Koropchak and M. Veber, Crit. Rev. Anal. Chem., 1992, 23, 113 Search PubMed.
  27. J. A. Koropchak, H. Aryamanya-Mugisha and D. H. Winn, J. Anal. At. Spectrom., 1988, 3, 799 RSC.
  28. S. K. Luo and H. Berndt, Spectrochim. Acta, Part B, 1994, 49, 485 CrossRef.
  29. R. Rubio, A. Padró, J. Albertí and R. Rauret, Anal. Chim. Acta, 1993, 283, 160 CrossRef CAS.
  30. M. A. Quijano, A. M. Gutiérrez, M. C. Pérez-Conde and C. Cámara, J. Anal. At. Spectrom., 1996, 11, 407 RSC.
  31. A. Sanz-Medel, B. Aizpun, J. M. Marchante, E. Segovia, M. L. Fernandez and E. Blanco, J. Chromatogr. A, 1994, 683, 233 CrossRef CAS.
  32. E. H. Larsen and S. Stürup, J. Anal. At. Spectrom., 1994, 9, 1099 RSC.
  33. P. Allain, L. Jaunault, Y. Mauras, J. Mermet and T. Delaporte, Anal. Chem., 1991, 63, 1497 CrossRef CAS.
  34. J. Goossens, F. Vanhaecke, L. Moens and R. Dams, Anal. Chim. Acta, 1993, 280, 137 CrossRef.
  35. F. Vanhaecke, J. Riondato, L. Moens and R. Dams, Fresenius' J. Anal. Chem., 1996, 355, 397 CAS.
  36. K. A. Vermeiren, P. D. P. Taylor and R. Dams, J. Anal. At. Spectrom., 1988, 3, 571 RSC.
  37. E. H. Larsen, G. Pritzl and S. H. Hansen, J. Anal. At. Spectrom., 1993, 8, 557 RSC.
  38. B. S. Sheppard, W. Shen, J. A. Caruso, D. T. Heitkemper and F. L. Fricke, J. Anal. At. Spectrom., 1990, 5, 431 RSC.
Click here to see how this site uses Cookies. View our privacy policy here.