Sandra Monti, Salvatore Sortino, Guido De Guidi and Giancarlo Marconi
The photochemistry of ketoprofen (KPF), 2-(3-benzoylphenyl)propionic acid, has been studied in aqueous solutions by time resolved (picosecond and nanosecond) spectroscopic techniques. Excited-state calculations were performed. The overall reactivity of the molecule was rationalized within a scheme in which the lowest triplet state can undergo intramolecular electron transfer and photoionization. The main pathway for the formation of the decarboxylated photoproducts was shown to involve intramolecular electron transfer and to pass through triplet biradicals.