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DOI: 10.1039/A700196G (Paper) Reference Section for: J. Chem. Soc., Dalton Trans., 1997, 1797-1800

A long-lived ascorbate radical in the platinum(II) catalysed reductions of platinum(IV) antitumor drugs

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Rathindra N. Bose and Evelyne L. Weaver

Abstract

A long-lived ascorbate radical was characterized during the reduction of a series of platinum(IV) antitumor drugs; ascorbate reductions proceed through a platinum(IV)–ascorbate intermediate, the formation of which is catalysed by platinum(II).

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