Biologically active pyridine mono- and bis-phosphonates: efficient ligands for co-ordination of Cu2+ ions

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Bogdan Boduszek, Marcin Dyba, Małgorzata Jeżowska-Bojczuk, Tamas Kiss and Henryk Kozłowski


Abstract

Potentiometric and spectroscopic studies on the co-ordination ability of biologically important pyridine mono- and bis-phosphonates have shown that when sterically possible these compounds undergo tridentate co-ordination with Cu2+ ions. The complexes obtained are very stable. When the position of the nitrogen donor is sterically unfavourable the major binding occurs at the bis(phosphonate) site.


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