Bifunctional catalytic membrane containing Brønsted acids and sites for enantioselective hydrogenation

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Diedrik Tas, Carla Thoelen, Ivo F. J. Vankelecom and Pierre A. Jacobs


Abstract

The hydrogenation of methyl acetoacetate to give optically pure methyl 3-hydroxybutyrate is performed hetero-geneously with high activity and enantioselectivity under mild reaction conditions due to the combination of Brønsted acid and Ru–binap sites in a polydimethylsiloxane membrane matrix.


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