A versatile approach to pyrimidin-4-yl substituted α-amino acids from alkynyl ketones; the total synthesis of l-lathyrine

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Robert M. Adlington, Jack E. Baldwin, David Catterick and Gareth J. Pritchard


Abstract

A range of pyrimidin-4-yl substituted α-amino acids has been synthesised by the reaction of amidines with α-amino acid alkynyl ketones.


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