Synthesis of optically active allenes using tandem enzyme and palladium-catalysed reactions

Abstract

The propargylic carbonates (S)-6 and (R)-9 are converted into the chiral allenes 10, 11, 13 and 14 (ee 82–85%) using organozinc reagents and tetrakis(triphenylphosphine)- palladium as catalyst.

References

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