An enantioselective synthesis of 2-alkyl-3-phenyltropanes by an asymmetric 1,3-dipolar cycloaddition reaction

Abstract

A method for gaining access to 2-alkyl-3-phenyl-substituted tropanes using the chiral dipolarophile (R)-p-tolyl vinyl sulfoxide in the asymmetric 1,3-dipolar cycloaddition reaction with the oxidopyridinium betaine 4 is described.

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