First total synthesis of (±)-hyperolactone A

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Daisuke Ichinari, Toshihiko Ueki, Kazuo Yoshihara and Takamasa Kinoshita


Abstract

The first total synthesis of (±)-hyperolactone A, isolated from Hypericum chinense L., is accomplished from 3-furoic acid and 2-methylbutanal.


References

  1. (a) M. Tada, M. Nagai, C. Okumura, Y. Osano and T. Matsuzaki, Chem. Lett., 1989, 683 CAS; (b) Y. Aramaki, K. Chiba and M. Tada, Phytochemistry, 1995, 38, 1419 CrossRef CAS.
  2. T. Kinoshita, D. Ichinari and J. Sinya, J. Heterocycl. Chem., 1996, 33, 1313 CAS.
  3. E. Vedejs and S. Larsen, Org. Synth., 1990, Coll. Vol. VII, 277.
  4. F. A. Davis and O. D. Stringer, J. Org. Chem., 1982, 47, 1774 CrossRef CAS; F. A. Davis, L. C. Vishwakarma, J. M. Billmers and J. Finn, J. Org. Chem., 1984, 49, 3241 CrossRef CAS.
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