Gene sensor using ferrocenyl oligonucleotide

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Toshihiro Ihara, Masamichi Nakayama, Mitsuru Murata, Koji Nakano and Mizuo Maeda


Abstract

An electrochemical gene sensing system has been developed using a redox-active ferrocene-modified oligonucleotide and an oligonucleotide anchored on a gold electrode, both of which formed a sandwich-type ternary complex with the target DNA to give a redox current.


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