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DOI: 10.1039/A703226I (Paper) Reference Section for: Chem. Commun., 1997, 1329-1330

The photochemistry of lomefloxacin. An aromatic carbene as the key intermediate in photodecomposition

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E. Fasani, M. Mella, D. Caccia, S. Tassi, M. Fagnoni and A. Albini

Abstract

Irradiation of the 6,8-difluoroquinolone antibiotic lomefloxacin causes selective heterolytic defluorination from position 8 and leads to products rationalized as arising from the cation either via nucleophile addition or intramolecular carbene C–H insertion and hydrogen transfer.

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