Haem binding and catalytic activity of two-α-helix peptide annealed by trifluoroethanol

Abstract

A designed two-α-helix peptide His-2α binds effectively Fe^III–mesoporphyrin (haem) and enhances N-demethylase activity of the haem, when the 2α-helix structure is annealed by the addition of 10–20% trifluoroethanol.

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