Mechanism of oxygenation of vitamin K hydroquinone

Abstract

When the monoanion of vitamin K hydroquinone is treated with ¹⁸O₂ in THF, the product, vitamin K oxide, carries a full atom of ¹⁸O at the epoxide oxygen and partial incorporation (34%) of a second atom of ¹⁸O at the carbonyl oxygen, which is most reasonably ascribed to the dioxetane mechanism.

References

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