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DOI: 10.1039/A700336F (Paper) Reference Section for: Chem. Commun., 1997, 695-696

Synthesis of 7-deaza-8-bromo cyclic adenosine 5′-diphosphate ribose: the first hydrolysis resistant antagonist at the cADPR receptor

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Victoria C. Bailey, Jaswinder K. Sethi, Antony Galione and Barry V. L. Potter

Abstract

7-Deaza-8-bromo cyclic adenosine 5′-diphosphate ribose is synthesised from 7-deazaadenosine via 7-deaza-8-bromo nicotinamide adenine dinucleotide; it is both a more potent antagonist than the 8-bromo derivative and has the advantage of chemical and enzymatic hydrolytic stability.

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