View PDF Version
 
DOI: 10.1039/A608477J (Paper) Reference Section for: Chem. Commun., 1997, 723-724

Common factors in the mode of action of vancomycin group antibiotics active against resistant bacteria

(Note: The full text of this document is currently only available in the PDF Version )

Gary J. Sharman and Dudley H. Williams

Abstract

It is shown that a semisynthetic glycopeptide, with activity against vancomycin resistant bacteria, possesses (as do other glycopeptides active in this way) features which promote its dimerisation and membrane anchoring.

References

  1. A. P. Johnson, A. H. C. Uttley, N. Woodford and R. C. George, Clin. Microbiol. Rev., 1990, 3, 280 CAS.
  2. G. M. Eliopoulos, Eur. J. Clin. Microbiol. Infect. Dis., 1993, 12, 409 CAS.
  3. P. Courvalin, Antimicrob. Agents Chemother., 1990, 34, 2291 CAS.
  4. S. Dutka-Malen, B. Blaimont, G. Wauters and P. Courvalin, Antimicrob. Agents Chemother., 1994, 38, 1675 CAS.
  5. Hospital Infection Control Practices Advisory Commitee, Infect. Control Hosp. Epidemiol., 1995, 16, 105 Search PubMed.
  6. C. T. Walsh, Science, 1993, 261, 308 CAS.
  7. C. T. Walsh, S. L. Fisher, I.-S. Park, M. Prahalad and Z. Wu, Chem. Biol., 1996, 3, 21 CrossRef CAS.
  8. G. D. Wright and C. T. Walsh, Acc. Chem. Res., 1992, 25, 468 CrossRef CAS.
  9. T. I. Nicas, D. L. Mullen, J. E. Flokowitsch, D. A. Preston, N. J. Snyder, M. J. Zweifel, S. C. Wilkie, M. J. Rodriguez, R. C. Thompson and R. D. G. Cooper, Antimicrob. Agents Chemother., 1996, 40, 2194 CAS.
  10. G. J. Sharman, A. C. Try, R. J. Dancer, A. J. Maguire, M. A. Cooper and D. H. Williams, unpublished work.
  11. J. P. Mackay, U. Gerhard, D. A. Beauregard and D. H. Williams, J. Am. Chem. Soc., 1994, 116, 4581 CrossRef CAS.
  12. D. A. Beauregard, D. H. Williams, M. N. Gwynn and D. J. C. Knowles, Antimicrob. Agents Chemother., 1995, 39, 781 CAS.
  13. A. Malabarba, R. Ciabatti, R. Scotti, B. P. Goldstein, P. Ferrari, M. Kurz, B. P. Andreini and M. Denaro, J. Antibiot., 1995, 48, 869 CAS.
  14. J. P. Waltho, D. H. Williams, E. Selva and P. Ferrari, J. Chem. Soc., Perkin Trans. 1, 1987, 2103 RSC.
  15. J. C. J. Barna, D. H. Williams, D. J. M. Stone, T. C. Leung and D. M. Doddrell, J. Am. Chem. Soc., 1984, 106, 4895 CrossRef CAS.
  16. M. S. Westwell, U. Gerhard and D. H. Williams, J. Antibiot., 1995, 48, 1292 CAS.
  17. M. Schafer, T. R. Schneider and G. M. Sheldrick, Structure, 1996, 4, 1509 CrossRef CAS.
  18. G. M. Sheldrick, E. Paulus, L. Vértesy and F. Hahn, Acta Crystallogr., Sect. B, 1995, 51, 89 CrossRef.
  19. P. Groves, M. S. Searle, J. P. Mackay and D. H. Williams, Structure, 1994, 2, 747 CrossRef CAS.
  20. J. P. Waltho and D. H. Williams, J. Am. Chem. Soc., 1989, 111, 2475 CrossRef CAS.
  21. U. Gerhard, J. P. Mackay, R. A. Maplestone and D. H. Williams, J. Am. Chem. Soc., 1993, 115, 232 CrossRef CAS.
Click here to see how this site uses Cookies. View our privacy policy here.