Investigation of the inframolecular acid–base properties of d-myo-inositol 1,3,4,5-tetrakisphosphate and dl-myo-inositol 1,2,4,5-tetrakisphosphate

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Philippe Guédat, Gilbert Schlewer, Elisabeth Krempp, Andrew M. Riley, Barry V. L. Potter and Bernard Spiess


Abstract

The protonation processes of the individual phosphate groups in two regioisomeric inositol polyphosphates, D-myo-inositol 1,3,4,5-tetrakisphosphate and DL-myo-inositol 1,2,4,5-tetrakisphosphate, have been investigated by 31P NMR titration experiments; the results are compared to those from D-myo-inositol 1,4,5-trisphosphate.


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