DOI: 10.1039/A608238F
(Paper)
Reference Section for: Chem. Commun., 1997, 555-556
Synthesis of the isomers of (1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester. A new class of ligands for the dopamine transporter
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Mohan Thiruvazhi, Philip Abraham, Michael J. Kuhar and F. Ivy Carroll
Abstract
The syntheses of all four isomers of (1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester are described; the 2β,3β-isomer shows high affinity for the cocaine binding site on the dopamine transporter.
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