Synthetic ribofuranose-containing polymers show catalytic activity in the hydrolysis of phosphodiesters

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Man Jung Han, Kyung Soo Yoo, Tae Joon Cho, Ji Young Chang, Yu Jin Cha and Seok Hyun Nam


Abstract

Synthetic polymers containing ribofuranose rings as pendent groups catalyse the cleavage of DNA and the hydrolysis of phosphodiesters with a rate acceleration of 103 compared with that of the uncatalysed reactions.


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