DOI: 10.1039/A607412J
(Paper)
Reference Section for: Chem. Commun., 1997, 97-98
Biosynthesis of macrophomic acid: plausible involvement of intermolecular Diels–Alder reaction
(Note: The full text of this document is currently only available in the PDF Version )
Hideaki Oikawa, Kenji Yagi, Kenji Watanabe, Mamoru Honma and Akitami Ichihara
Abstract
The biosynthetic precursor of the fungal metabolite macrophomic acid 4 from Macrophoma commelinae has been studied by feeding experiments and enzymatic conversion from the pyrone 3 to 4 in a cell-free system. Based on the experimental data, a biosynthetic pathway for 4 involving an unprecedented intermolecular Diels–Alder reaction is proposed.
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