A novel hydride rearrangement of the acetal group of tetraacetal tetraoxa-cages mediated by Lewis acids

Abstract

Treatment of tetraoxa-cages 1a–f with Lewis acids such as TiCl₄, AlCl₃, BF₃·OEt₂ and MeSO₃H in dichloromethane at 25 °C gives the rearrangement products 2a–f in 90% yields regioselectively and stereoselectively; a novel hydride rearrangement of the acetal group of tetraacetal tetraoxa-cages mediated by Lewis acids.

References

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