DOI: 10.1039/A703175K
(Paper)
Reference Section for: Analyst, 1997, 122, 1087-1088
Step-gradient Capillary Electrochromatography
(Note: The full text of this document is currently only available in the PDF Version )
Melvin R. Euerby, Declan Gilligan, Christopher M. Johnson, Melvin R. Euerby and Keith D. Bartle
Abstract
The analytical benefits of using a step-gradient in capillary electrochromatography (CEC) are demonstrated. The application of step-gradient CEC to the analysis of six diuretics of widely differing lipophilicities was evaluated and shown to result in a marked reduction in the analysis time and an improvement in the peak shape for later-eluting lipophilic components. When the step-gradient approach was performed in an automated mode, the retention time RSD for repeated injections was below 1%.
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