View PDF Version
 
DOI: 10.1039/A701257H (Paper) Reference Section for: Analyst, 1997, 122, 771-776

Near-infrared Reflectance Spectrometry in the Studyof AtopyPart 2. Interactions Between the Skin and Polyethylene Glycol 400, Isopropyl Myristate and Hydrogel

(Note: The full text of this document is currently only available in the PDF Version )

E. Dreassi, G. Ceramelli, P. Mura, P. L. Perruccio, F. Vocioni, P. Bartalini and P. Corti

Abstract

An investigation into the existence of spectral differences and differences in response in terms of water and lipid content between normal and atopic skin after interaction with chemical agents is described. Three compounds were taken as models: a prevalently hydrophilic solvent (polyethylene glycol, PEG 400), a prevalently lipophilic solvent (isopropyl myristate) and a hydrophilic pharmaceutical (gel) used to promote contact in electrocardiography. Using principal component analysis it was possible to distinguish atopic and normal subjects by simple contact of the skin with chemical agents.

References

  1. R. O. Potts, D. B. Guzek, R. R. Harris and J. E. McKie, Arch. Dermatol. Res., 1985, 277, 489 CrossRef CAS.
  2. V. H. W. Mak, R. O. Potts and R. H. Guy, J. Controlled Release, 1990, 12, 67 CrossRef CAS.
  3. D. Bommannan, R. O. Potts and R. H. Guy, J. Controlled Release, 1991, 16, 299 CrossRef CAS.
  4. G. M. Golden, D. B. Guzek, R. R. Harris, J. E. McKie and R. O. Potts, J. Invest. Dermatol., 1986, 86, 255 CrossRef CAS.
  5. G. M. Golden, J. E. McKie and R. O. Potts, J. Pharm. Sci., 1987, 76, 25 CAS.
  6. P. Corti, L. Savini, E. Dreassi, G. Ceramelli, L. Montecchi and S. Lonardi, Pharm. Acta Helv., 1992, 67, 57.
  7. P. Corti, L. Savini, E. Dreassi, S. Petriconi, R. Genga, L. Montecchi and S. Lonardi, Process Control Qual., 1992, 2, 131 CAS.
  8. E. Dreassi, G. Ceramelli, L. Savini, P. Corti, P. L. Perruccio and S. Lonardi, Analyst, 1995, 120, 319 RSC.
  9. E. Dreassi, G. Ceramelli, P. Corti, S. Lonardi and P. L. Perruccio, Analyst, 1995, 120, 1005 RSC.
  10. E. Dreassi, G. Ceramelli, P. Corti, M. Massacesi and P. L. Perruccio, Analyst, 1995, 120, 2361 RSC.
  11. E. Dreassi, G. Ceramelli, P. Corti, P. L. Perruccio and S. Lonardi, Analyst, 1996, 121, 219 RSC.
  12. P. Mura, A. Liguori, G. Bramanti, P. Corti, C. Murratzu and L. Celesti, Pharm. Acta Helv., 1990, 65, 298 CAS.
  13. L. Celesti, C. Murratzu, M. Valoti, P. Corti and G. P. Sgaragli, Methods Find. Exp. Clin. Pharmacol., 1992, 14, 701 Search PubMed.
  14. L. Celesti, C. Murratzu, M. Valoti, G. P. Sgaragli and P. Corti, Methods Find. Exp. Clin. Pharmacol., 1993, 15, 49 Search PubMed.
  15. P. Mura, L. Celesti, M. Valoti, P. Corti and P. Santoni, Eur. J. Pharm. Biopharm., 1994, 40, 90 CAS.
  16. P. Mura, L. Celesti, D. Proietti, S. Corsi, S. Furlanetto and P. Corti, Acta Tecnol. Legis Med., 1993, 4, 121 Search PubMed.
  17. P. Mura, C. Nassini, D. Proietti, A. Manderioli and P. Corti, Pharm. Acta Helv., 1995, 70, 175 CrossRef CAS.
Click here to see how this site uses Cookies. View our privacy policy here.