(Z)-Heptadec-8-enylboronic acid, a potential lipase inhibitor that is isosteric with oleic acid, and that is unexpectedly sensitive to aerial oxidation, has been prepared in 23% overall yield from dec-1-yne and 7-bromoheptanol. Disappointingly, the target compound proved inactive under conditions where lipase inhibition would have been expected.
V. Martichonok and J. B. Jones, J. Chem. Soc., Perkin Trans. 1, 1995, 2927 DOI: 10.1039/P19950002927
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