Facile, general and productive syntheses of the fluorescent wye (4,9-dihydro-4,6-dimethyl-9-oxo-1H-imidazo[1,2-a]purine) in phenylalanine tRNA, its 2-substituted derivatives and 7-aza analogues

Abstract

Novel syntheses of 4,9-dihydro-4,6-dimethyl-9-oxo-1H-imidazo[1,2-a]purine (Y base skeleton), its 2-substituted derivatives and 7-aza analogues and their fluorescence characteristics in relation to their structures are described.