Racemic 2-hydroxymethylthieno[3,2-e:4,5-e′]di[1]benzothiophene with a labile helical structure was converted into a (P) enantiomer upon uptake by bovine serum albumin, in which the existence of two substrate-binding sites with a distinct ability to recognize chirality was revealed.
K. Yamada, R. Ishii, H. Nakagawa and H. Kawazura, J. Chem. Soc., Chem. Commun., 1994, 1521 DOI: 10.1039/C39940001521
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