Asymmetric hydroformylation of 1,2-disubstituted olefins catalysed by chiral phosphinephosphite–rhodium(I) complexes

Abstract

Hydroformylations of internal olefins such as (E)- and (Z)-but-2-ene, (E)- and (Z)-1-phenylprop-1-ene, indene, and 1,2-dihydronaphthalene catalysed by (R,S)-binaphos–Rh^I complex {(R,S)-binaphos =(R)-[2-(diphenylphosphino)-1,1′-binaphthalen-2′-yl][(S)-1,1′-binaphthalen-2,2′-diyl]phosphite} or its enantiomer gave the corresponding oxoaldehydes in up to 97% enantiomeric excess, e.e.