Issue 4, 1994

Preparation of activated nucleotides and their phosphorothioate and phosphorodithioate analogues

Abstract

The preparation of nucleoside phosphoro-(1,2,4-triazolides)(e.g.9a) and their thio-and dithio-analogues (e.g.9b and c, respectively), and a corresponding set of activated nucleotides (e.g.10a, b, c) derived from 1-hydroxybenzotriazole is described; the reactions between these derivatives and methylamine are also reported.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1994, 385-387

Preparation of activated nucleotides and their phosphorothioate and phosphorodithioate analogues

C. B. Reese, L. H. K. Shek and Z. Zhao, J. Chem. Soc., Chem. Commun., 1994, 385 DOI: 10.1039/C39940000385

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