The compatibility of an anti-emetic with the chloride ion of an analgesic has been investigated by means of high-performance liquid chromatography and ultraviolet–visible spectrophotometry. The solubility of the anti-emetic, cyclizine, has been shown to deviate from theoretical values as a result of supersaturation and the effect of counter ions.
P. J. Dwyer, P. J. Weir, D. S. Ireland and C. G. Taylor, Anal. Proc., 1994, 31, 157 DOI: 10.1039/AI9943100157
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