Issue 20, 1993

1,3-Dipolar cyctoadditions of 4,5-dihydroimidazolium ylides: new protocols for the synthesis of pyrrolidines and pyrrolo[1,2-a]pyrazines

Abstract

1,3-Dipolar cycloadditions of 4,5-dihydroimidazolium ylides formed from 1-benzyl-4,5-dihydroimidazole proceed via a convenient one-step, one-pot protocol to give hexahydropyrrolo[1,2-a]imidazole esters, reduction of which leads to either hexahydropyrrolo[1,2-a]pyrazines or N-substituted pyrrolidines depending on the nature of the ester.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1993, 2391-2393

1,3-Dipolar cyctoadditions of 4,5-dihydroimidazolium ylides: new protocols for the synthesis of pyrrolidines and pyrrolo[1,2-a]pyrazines

R. C. F. Jones and K. J. Howard, J. Chem. Soc., Perkin Trans. 1, 1993, 2391 DOI: 10.1039/P19930002391

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