Novel double functional group transformation: ‘one-flask’ conversion of 1-nitrocycloalkenes to terminally unsaturated nitriles
Abstract
A new method has been developed for the conversion of 1-nitrocycloalkenes to terminally unsaturated nitriles in one flask by use of Me3SiCH2MgCl (1.8 equiv.) and PCl3(2.5 equiv.) in tetrahydrofuran.