Issue 7, 1993

A highly convergent strategy towards rapamycin. Stereoselective construction of the C8–C18 fragment

Abstract

A strategy for a total synthesis of the immunosuppressant agent rapamycin 1 is outlined and the stereoselective construction of a suitably functionalized C8–C18 fragment 2 is described.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1993, 617-618

A highly convergent strategy towards rapamycin. Stereoselective construction of the C8–C18 fragment

A. D. Piscopio, N. Minowa, T. K. Chakraborty, K. Koide, P. Bertinato and K. C. Nicolaou, J. Chem. Soc., Chem. Commun., 1993, 617 DOI: 10.1039/C39930000617

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