Furans have been efficiently synthesised by a three-step reaction sequence. Michael addition of keto esters to alkenyl sulfoxides followed by Pummerer rearrangement afforded the cyclic intermediates 11 in good yield. Treatment of the latter with 2-chloroperoxybenzoic acid led by oxidation and syn-elimination of the corresponding sulfoxide, to substituted furans.
W. H. Chan, A. W. M. Lee and E. T. T. Chan, J. Chem. Soc., Perkin Trans. 1, 1992, 945 DOI: 10.1039/P19920000945
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