Interactions between metal cations and the ionophore lasalocid. Part 11.—Equilibria of lasalocid alkali-metal salts in water and water–chloroform systems

Abstract

Alkali-metal complex salts of the ionophore lasalocid are shown to be slightly soluble in pure water and aqueous phases. Both the ionic solubility products and the solubilities of the neutral undissociated forms of these salts are obtained. Their association constants in water are thus calculated and their partition constant between water and chloroform estimated. These various results are discussed in terms of solvation and structure of the species involved. Relevant biological functional aspects are also considered.