Metabolism of bromobenzene and iodobenzene by growing cultures of Pseudomonas putida UV4 gave the corresponding cis-dihydrodiol products 1 and 2 in high yields; subsequent direct chemical substitution of the halogen atoms in these metabolites provided a new range of enantiomerically pure cis-dihydrodiols of known absolute configuration.
D. R. Boyd, M. V. Hand, N. D. Sharma, J. Chima, H. Dalton and G. N. Sheldrake, J. Chem. Soc., Chem. Commun., 1991, 1630 DOI: 10.1039/C39910001630
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