A new and relatively simple method involving Pd0-catalysed cross coupling of acid chlorides and β-stannyl alkenoates provides an efficient route to γ-oxo-α,β-unsaturated macrolides.
J. E. Baldwin, R. M. Adlington and S. H. Ramcharitar, J. Chem. Soc., Chem. Commun., 1991, 940 DOI: 10.1039/C39910000940
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