syn-Selectivity in the epoxidation of 1-(cyclohex-2-enyl)-2-nitroimidazole mediated by hydrogen bonding
Abstract
Epoxidation of 1-(cyclohex-2-enyl)-2-nitroimidazole with 3-chloroperoxybenzoic acid occurs exclusively syn to the nitroimidazole in the absence of water; amines react only with the syn epoxide.