Dehydrochlorination of hydroximic acid chlorides by the use of organotin compounds: an application for synthesis of isoxazolines and isoxazoles
Abstract
The reactions of hydroximic acid chlorides and organotin compounds such as bis(tributyltin) oxide or tetraphenyltin, whereby nitrile oxides are generated effectively, are applied to the preparations of isoxazolines and isoxazoles via[3 + 2] dipolar cycloaddition.