Rearrangement of rel-(4aR,7S,7aR,13S)1,2,3,4,4a,5,6,7,7a,12-decahydro-7-phenylisoindolo[1,2-d]quinolizin-13-ium tosylate to rel-(5S,6R,10R,13S)-5,6,7,8,9,10,11,12,13,14-decahydro-13-phenyl-5,6,10-nitrilobenzocyclododecene

Abstract

Treatment of rel-(4aR,7S,7aR,1 3S)1,2,3,4,4a,5,6,7,7a,12-decahydro-7-phenylisoindolo[1,2-d]-quinolizin-13-ium tosylate with lithium aluminium hydride gave rel-(5S,6R,10R,13S)-5,6,7,8,9,10,11,12,13,14-decahydro-13-phenyl-5,6,10-nitrilobenzocyclododecene. An X-ray structural analysis of the product was performed.