A synthesis of micandrol-C a novel methylthiophenanthrenediol isolated from the trunkwood of Micandropsis scleroxylon
Abstract
The structure of the unusual phenanthrene micandrol-C (7-methyl-1-methylthiophenanthrene-2,6-diol)(16), isolated from the trunkwood of the Amazonian tree, Micandropsis scleroxylon W. Rodr., is confirmed by synthesis. The key step involved the cyclization of a cis-2-chlorostilbene in the presence of activated magnesium.