A cis-diaqua copper(II) complex, (1), has been shown to be active in catalysing the hydrolysis of formamide, N-methylformamide, and N,N-dimethylformamide in neutral water at 100 °C; monoaqua copper(II) complexes are not active in catalysing the hydrolysis of the amides under the same conditions.
J. Chin, V. Jubian and K. Mrejen, J. Chem. Soc., Chem. Commun., 1990, 1326 DOI: 10.1039/C39900001326
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